Intra-uterine Insemination IUI
This procedure is normally performed when the fallopian tubes and the husband’s sperm are normal, the wife is very young and the period of infertility is short.
The ovulation induction is normally done with much simpler drug regimen (tablets and / or few injections). If clomiphene citrate or Letrozole is given, it is taken from day 2 to day 6 of the menstrual cycle. A few injections may also be added. Follicular monitoring is started from day 9 by ultrasound scans. The aim is to produce one or two follicles only. Normally ultrasound scans are done but sometimes blood tests are requested to ascertain the hormone status. Once the follicles have reached the optimal maturity then the timed injection of human chorionic gonadotrophin (hCG) is given to trigger ovulation. Ovulation normally takes place 36-40 hours after the injection. You are asked to come to the centre on the day of ovulation in the morning. If there is any doubt a repeat scan may be done to confirm follicular rupture and ovulation.
The husband will provide the semen specimen to the IVF laboratory in the morning which is then processed (washing and swim-up) which takes about three hours. The prepared sperm specimen is injected into the uterine cavity using a special catheter. After the IUI you could go home after 10 minutes and carry on with normal activity. Hormonal support is given to maintain the uterine lining (endometrium) in the optimal state to increase the chances of a pregnancy.